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Laboratory studies have demonstrated biological activity at concentrations as low as 0.01 nanomolar, showing measurable effects on fibroblast activity and collagen production even at these minute levels

When the researchers aspirated and analyzed the participants stomach contents, they found that in meals containing one to six grams of gluten, the enzyme digested an average of at least 97 percent of the gluten by 20 to 35 minutes after drug administration

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10.1073/pnas.95.15.8892 104 MattiazziM.D'AurelioM.GajewskiC