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While in vitro and in vivo models cannot fully replicate human physiology, it remains critical to simulate realistic biological conditions as realistically as possible

Vitamin B12 (cobalamin) is a water-soluble vitamin required for DNA synthesis, red blood cell formation, myelin maintenance, and methylation the biochemical process that regulates gene expression, neurotransmitter production, and homocysteine metabolism

Avila, M

Epigenetic mechanisms in the pathogenesis of diabetic foot ulcers

Lifestyle and diet People who eat glutathione-rich fruits and foods, exercise, and sleep well may still maintain better levels even without supplements

The rationale for combining them is that they may act through complementary repair pathways