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Bacteria boost mammalian host NAD metabolism by engaging the deamidated biosynthesis pathway

(2019a) reported 8 g CM ingestion 2 h prior to exercise had no effect on muscle blood flow (CM: 3.78 0.26, placebo: 3.72 0.26 ml.min 1 .100 ml 1 ) or oxygen consumption (CM: 1.15 0.11, placebo: 1.16 0.11 mLO 2 .min 1 .100 g 1 ) during 3 min of leg extension exercise (one rep every 4 s)

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Notably, ROS can react with unsaturated lipids to form lipid peroxides such as malondialdehyde, 4-hydroxy-2-nonenal (4-HNE), and acrolein, further exacerbating oxidative stress [30, 31]