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Morbidity The comorbid impact of weight loss on older adults can be collectively considered by its musculoskeletal and metabolic impact with physiological effects on different tissues such as skeletal muscle and bone, and on cardiovascular and metabolic function

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Moreover, carriers of CYP2C9*3 allelic variant, CYP2A6*1/*4 and CYP2A6*4/*4 genotypes, had elevated hepatotoxic levels of 4-en-VPA and/or 2,4-diene-VPA compared to homozygous carriers of the wild-type allele CYP2A6*1/*1 [68]

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Comparable findings were achieved at Renmin Hospital of Wuhan University, where a study involved 651 people diagnosed with MetS and 727 healthy individuals