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Side effect management GLP-1 medications come with a predictable set of side effects that most users experience to some degree

Key Takeaways Tirzepatide activates two incretin hormone pathways (GLP-1 and GIP)

Patients with pre-existing diabetic retinopathy should be aware that rapid improvement in blood glucose can sometimes temporarily worsen retinopathy and should report any visual changes promptly

These terms change frequently enough that any figure published in an article is likely to be stale by the time it is read

Serious adverse events have not been widely reported, but this may reflect the relatively small number of people who have used the compound and the limited reporting mechanisms available