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The binding constant of GHK for copper (log10 = 16.44) slightly exceeds that of albumin (log10 = 16.2), enabling the peptide to acquire Cu2+ from plasma proteins and deliver it to cells while silencing coppers potentially damaging redox activity (Pickart, 1977)

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Also promising is the usage of these imaging modalities in the selection of patients that may benefit from an extended time window of intravenous thrombolysis (176) and in the early detection of patients that may develop severe stroke complications such as HT, which would be key in the specific guided treatment of AIS patients avoiding, therefore, poorer prognosis and adverse clinical developments (154)

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Effects of TZD Use and Discontinuation on Fracture Rates in ACCORD Bone Study

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