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Clinicians ought to tailor therapies, approach peptides as complementary not curative, and evaluate response and safety with biomarkers and clinical surveillance

This network potentially maintains the disease course and shapes inflammation in the CNS, which is essential for initiating and dominating the progressive phase of MS

Anecdotal evidence and pharmacoepidemiological studies in humans report reduced alcohol use by patients using GLP-1RAs for other indications

Importantly, the QMP-engineered GLP-1 albumin fusion did not only display improved PK properties, but also demonstrated a prolonged therapeutic effect in healthy human FcRn Tg32 mice challenged with a high dose of glucose

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doi: 10.1016/j.redox.2022.102463