Gallbladder conditions, including gallstones and inflammation, have also been observed at higher rates in Ozempic users during clinical trials
This is different from GLP-1s mechanism, which primarily reduces the drive to eat and the reward value of food through hypothalamic and mesolimbic circuits
GLP-1 receptor activation enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, slows gastric emptying, and reduces appetite through central nervous system effects
During week 4 I tried to focus on getting back into consistent exercise to help things along since I felt like I had plateaued
Excessive incretin hormones may also contribute to pancreatic islet cell hyperplasia, leading to hyperinsulinism
Calcium citrate is preferred for GLP-1 users because it does not require stomach acid for absorption, which matters when gastric acid production may be altered