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Intervention trials Community-based studies An early intervention trial of selenium supplementation was undertaken in China in 1985 among a general population of 130,471 individuals living in a high-risk area for viral hepatitis B infection and liver cancer

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showed that markers of an impaired barrier function associated with bacterial translocation as LPS and LBP are increased in the serum of CD patients with active and inactive disease whereas they are only increased in UC patients with active disease

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