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2016;353:i1753

Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle

References (1) Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH

Research reveals that senescent cells show upregulation of pro-apoptotic initiators PUMA and BIM while anti-apoptotic guardian BCL-2 is reduced, suggesting these cells are ready to undergo apoptosis but the execution is restrained by the FOXO4-p53 interaction

It is composed of 15 amino acids, is a partial sequence of body protection compound that is discovered in and isolated from the human gastric juice