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Vadher K, Patel H, Mody R et al (2022) Efficacy of tirzepatide 5, 10 and 15 mg versus semaglutide 2 mg in patients with type 2 diabetes: an adjusted indirect treatment comparison

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3B), semaglutide-treated mice showed reduction of thermogenesis-related genes ( Ucp1 and Pgc1a ) and Cpt1b , suggesting decreased thermogenic and oxidative activity