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Managing meal size, food choices, and hydration can significantly reduce discomfort

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Some treatments used in mild to moderate cases of RLS are targeted at lifestyle changes such as: Beginning regular exercise Developing good sleeping patterns/habits Reducing the use of stimulants Reducing the consumption of alcohol and tobacco Non-lifestyle treatment methods include: Leg massages Hot baths and/or ice packs A vibrating pad In some cases drugs may be used, but the effects may relieve or worsen your RLS (results are sporadic) and the effectiveness may lessen over time

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The sultr4;1 and sultr4;2 mutants impaired in mediating the efflux of sulfate from vacuoles to the cytoplasm 67 displayed also WT-like growth under AITC treatment