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Clinical trials at doses up to 40mg daily for 12 weeks have reported no serious adverse effects (Brendler & Williamson, 2019, Phytomedicine )

Figure 1 Primary BAs are essential for lipid/vitamin digestion and absorption (Joyce and Gahan, 2016

In this experimental setting, atrophy was evident in soleus muscle, but was absent in extensor digitorum longus (EDL) muscle, following 91 days of long-term exposure to real microgravity in space

Attia, M

Relevant to the subject, Sweden has a free prescription right which means that a prescriber can, at his or her own discretion but judging it based on scientific evidence and proven experience, circumvent, e.g., the approved indication and prescribe a drug outside of the specifications in the Summary of Product Characteristics (SmPC), i.e., off-label