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The glutathione pathway may also supply glutamate when glia derived glutamine is blocked by MeAIB, which inhibits system A transporters

TB-500, the synthetic analogue of Thymosin Beta-4 (T4), is a 43-amino acid peptide originally isolated from calf thymus

They have neuroprotective effects in humans, reducing disease progression by protecting neurons from oxidative damage, A-induced neuronal injury and neurotoxicity, and nitric oxide-induced toxicity while increasing neuronal function and regeneration and modulating neuronal signaling pathways [20,28]