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Sponsors can supplement these with data from new approach methodologies given appropriate scientific justification

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Cardiovasc Res 43(3):521531 Rosales MA et al (2014) S-nitrosoglutathione inhibits inducible nitric oxide synthase upregulation by redox posttranslational modification in experimental diabetic retinopathy

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Inhibiting zinc transporters or chelating zinc can disrupt vital processes for cancer cell survival and proliferation, displaying potential as an anticancer strategy

Glucagon Release Reducing Glucose Release: GLP-1 helps decrease the amount of released glucagon during digestion, resulting in less glucose production