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However, Novo Nordisk pointed out that the study primarily focused on diabetes patients taking a low dose of semaglutide, rather than typical weight-loss use, for which the company's higher-dose Wegovy pill is approved

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Age distribution shows peak usage in the 35-65 year age range, though prescription rates among adults under 35 are accelerating rapidly due to direct-to-consumer marketing and telehealth platforms

In addition, NADPH generation via glutamine metabolism in cancer cells supports redox homeostasis by maintaining the cytosolic NADPH pool used to restore oxidized glutathione 29 (Fig