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95% confidence interval (CI): 0.780.99)

Typical rule: Maximum stack size 2 compounds Never introduce multiple compounds simultaneously

Full evaluation of hair results requires 6 months minimum

Do not let one uncertain injection spiral into weeks of second-guessing

A suggestive albeit non-significant difference in absolute HbA1c lowering was observed in heterozygous carriers of p.D563G after GLP-1RA initiation (-0.25% (2.7 mmol/mol) per allele, p = 0.050)

The available data remain largely preclinical or based on limited observations, and its non-selectivity is also its main limitation: by affecting multiple receptors, it is associated with varied effects reported in the literature