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This means they can potentially cause a blood sugar spike, followed by an energy crash and increased hunger

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Regarding oral contraceptives specifically, a clinically relevant interaction with delayed gastric emptying has been documented for tirzepatide in its UK Summary of Product Characteristics (SmPC), which advises the use of a non-oral or additional contraceptive method during initiation and dose escalation

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[31] [32] [33] [34] Society and culture [edit] Legal status [edit] In May 2026, the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Ablymico, indicated for weight management as an adjunct to a reduced-calorie diet and increased physical activity

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Burrus B.M., Moscicki B.M., Matthews T.D., Paolone V.J