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Some people who had well-managed bowel function on tirzepatide experience temporary constipation or diarrhea during the switch as their digestive system adjusts to the new pattern of gut motility signals

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However, the same active drug, semaglutide, is available as a daily oral tablet called Rybelsus, which is a different product approved for type 2 diabetes

By promoting weight reduction, semaglutide improves metabolic parameters, including blood pressure, cholesterol levels, and insulin sensitivity, thereby reducing the risk of cardiovascular events

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