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Pharmacological interventions are indicated in patients with a BMI 30 kg/m 2 or 27 kg/m 2 in the presence of 1 obesity-related comorbidities 10

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The patient's metabolic rate determines the response

However, there is a need to standardize parameter measurements (such as TEWL, collagen density, viscoelasticity, etc.) in randomized, placebo-controlled trials in designs that include estrogen-deficient skin in menopausal women with correlations to biomarkers examined in these clinical studies that assist patients and physicians as to how to evaluate, select, and provide the most effective treatments in the future

Sources 1 Dubin AE, Patapoutian A