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For the patients using bupropion-naltrexone, just one had pancreatitis, two had bowel obstruction, and three had gastroparesis
This mechanism is separate from how antidepressants functionmost antidepressants work by increasing serotonin, norepinephrine, or dopamine levels in the central nervous system
Journal of Aerosol Science 42 (2), 100113 (2011)
Both trials suggest maintenance strategies, such as lower-dose injections or oral therapies, could offer patients more flexible, potentially more convenient options for sustaining weight loss after intensive treatment
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