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The final reported protein FDR was 0.01 (based on the target-decoy approach)

Ellagic acid inhibits key epigenetic enzymes, EZH2 and PRMT5:MEP50, with strong binding affinities, reducing their catalytic products, H3K27me3 and H4R3me2s [74]

(4) Research has demonstrated that NNMT inhibition results in increased intracellular nicotinamide and SAM levels

As wound healing is essential to tissue integrity and overall health, the care and management of chronic wounds in aging populations have become a critical public health concern, annual cost of treating chronic wounds, including various ulcers, are estimated to reach up to $96 billion in the U.S

10.1002/hep.28537 Hepatology 3 AguirreL.HijonaE.MacarullaM

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