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Reported side effects in human anecdotal use are generally mild and may include: Mild nausea, particularly with oral administration Redness, itching, or irritation at the injection site Temporary dizziness or mild headache Changes in appetite or weight A significant theoretical concern revolves around its pro-angiogenic properties

Prostaglandin H 2 is converted to vasoactive molecules, such as PGI 2

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A low NAD+ to NADH ratio has been linked to mitochondrial dysfunction and accelerated ageing