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In the dorsal root ganglion (DRG), hyperglycemia leads to reduced synthesis of neurofilament, GAP43 and -tubulin, alongside an increased expression of stress-related proteins (HSP and PARP)

Med Sci Monit 23:54105419 Sun HX, Lu N, Luo X, Zhao L, Liu JM (2015) Liraglutide, the glucagon-like peptide-1 receptor agonist, has anabolic bone effects in diabetic Goto-Kakizaki rats

Furthermore, cell-specific transneuronal tracing indicated labeling from the vagal sensory ganglion to dopamine cells in the substantia nigra, but not to brain regions directly regulating locomotion 86

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However, clinicians should remain cautious and consider individual health profiles when recommending prolonged therapy

Semaglutide has been steadily expanding its clinical footprint, gaining U.S