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: Direct stimulation of 1 -Adrenergic Activation 1 -adrenergic receptors on myocytes increases myocardial chronotropy (heart rate) and inotropy (contractile force), thereby elevating or maintaining cardiac output (CO), depending on the dose used (Solanki et al, 2014)

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Physiol Rev 87:245313 Lennicke C, Rahn J, Lichtenfels R, Wessjohann LA, Seliger B (2015) Hydrogen peroxideproduction, fate and role in redox signaling of tumor cells