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iNOs/NO pathway It has been found that ferroptosis plays a role in different mammalian cells, but some specific types of cells, especially cells of the innate immune system (such as macrophages), show significant resistance to ferroptosis [44]

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The premature skin-aging effects of tobacco smoking are caused by induction of collagenase activity and the reduced blood flow to the skin due to nicotine-induced vasoconstriction