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Measurement ranges are 8.60 to approximately 2,000 nM

Excessive production of ROS not only directly damages cellular membranes, proteins, and DNA, but also activates inflammatory signaling pathways such as NF-B, thereby promoting the release of pro-inflammatory cytokines including TNF-, IL-1, and IL-6

804443) and 100 g/mL streptomycin (Reig Jofre S.A., Madrid, Spain

USA 91 , 1062510629 (1994)

This bidirectional relationship is clinically evident in the early elevation of OS biomarkers (e.g., urinary 8-OHdG, serum F2-isoprostanes) preceding overt DM and their correlation with disease severity and complications (e.g., retinopathy, nephropathy)

Peptides offer anti-inflammatory effects without global immunosuppression or catabolic tissue effects