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There was also a trend toward higher Gip expression in both sexes, which aligned with a recent report showing that insulin receptor signaling in IECs specifically regulates postprandial GIP but not GLP-1 (57)

Devi et al., 2022)

Meanwhile, other pharma giants have joined the race

Yet, the expression of this transporter in different parts of the gut (Figure 2B) does not exclude its possible participation in the guts absorption of ThDP from the diet, especially given the presence of other folate transporters on the brush border membrane of enterocytes, i.e., those encoded by SLC46A1, FOLR1, and FOLR2 (119)

NEJM , Jastreboff, Ania M., et al

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