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There is a discrepancy between the magnitude of improvement in glycemic control and the weight loss, cardiovascular, and renal benefits obtained in large clinical trials

Eating a diet containing yogurts, kimchi, miso soup, kombucha, and sauerkraut can help keep the gut microbiome optimized

[2] These typically improve over time

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A 2021 data analysis found that 40% of US adults aged 18 to 44 are insulin-resistant, showing it to be a likely cause of obesity for many people

Published evidence comparing drug costs to outcome measures for health insurers/systems remains sparse, but one study compared the treatment of type 2 diabetes with insulin versus treatment with GLP-1s and found that the higher drug and outpatient costs associated with GLP-1 treatment were offset by a reduction in healthcare costs from emergency visits and inpatient admissions