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Nauck MA et al

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(1982) 243:E1530

Recently, interest in the role of brain atrophy in reducing regional mass effect of space-occupying lesions has risen 9,10,11,12

In pancreatic cells, activation of these G proteincoupled receptors primarily signals through pathways involving cyclic adenosine monophosphate (cAMP), protein kinase A ( PKA ), and cAMP response elementbinding protein ( CREB ), thereby enhancing glucose-dependent insulin secretion and supporting -cell function