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Its recommended not to freeze (as mentioned) and also to avoid excessive heat

Certain medications The following drugs can reduce levels of vitamin B12 in your body: Antibiotics -- long-term use can lower vitamin B levels generally Anti-seizure drugs Chemotherapy medicines, especially methotrexate Drugs used to reduce stomach acid, like H2 blockers (Pepcid AC, Tagamet, Zantac) and proton pump inhibitors (Nexium, Prevacid, Prilosec) Metformin (Glucophage) -- taken for diabetes Colchicine -- taken for gout Some cholesterol-lowering medications Other causes You're over 65

This is why a personalized plan from a professional is so importantits tailored to what your body specifically needs to recover

That doesnt make these compounds useless for research the safety profile is well-established, the mechanism is plausible, and moderate fat loss with no hormonal disruption is a meaningful profile for the right researcher

Problems can also arise after intestinal or stomach surgeries are performed

doi:10.1016/bs.pbr.2021.01.023