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Gallbladder Disease (Cholelithiasis and Cholecystitis) Risk: Clinical trials have shown that treatment with semaglutide is associated with an increased risk of developing gallstones (cholelithiasis) and gallbladder inflammation (cholecystitis)

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human studies reported prolonged GH/IGF-1 elevation

In a completed phase 2b, randomized, double-blind, placebo-controlled trial 19 , we tested whether once-weekly semaglutide can slow epigenetic aging in PWH-associated lipohypertrophy, a population marked by visceral adiposity and accelerated epigenetic age

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