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48, 49 However, claudin-2 also serves other diverse functions including paracellular passage of cations (including sodium and calcium), cell proliferation and autophagy, and loss of claudin-2 along with claudin-15, yet another TJ protein implicated in paracellular Na + passage, results in premature death because of malnourishment in mice

Matrixyl (pal-KTTKS) currently has the most solid, face-specific clinical trial data among common cosmetic peptides

When p53 transcriptional activity in response to 5-FU treatment was measured, the mRNA and protein levels of p21, which is a p53 target gene, were decreased in the GST WT -p53-expressing cells

Consult with a healthcare provider about a possible vitamin B12 deficiency

If cyanide poisoning is suspected, treatment should not be delayed to obtain a plasma lactate concentration

Wallesch CW, Horn A