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Additionally, several key clinical trial readouts delivered compelling data across multiple indications, for example (see Figure 1): Semaglutide : STEP-HFpEF (functional benefits in HFpEF), STEP-9 (pain reduction in knee osteoarthritis), STEP-10 (reversion to normoglycaemia in pre-diabetic, obese patients), ESSENCE (resolution of MASH, improvement in fibrosis) Tirzepatide : SUMMIT (risk reduction in HFpEF outcomes

These studies could identify key enzymes involved in maintaining the cells redox balance

Seven in Absentia Homolog 2 (Siah2) protein is a regulator of NF-E2-related factor 2 (Nrf2)

High maternal fever and certain infections can influence fetal brain development

Researchers worry GLP-1s may actually intensify obesity stigma

Small swaps accumulate into big results