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34 Given the promising results of semaglutide 2.4 mg, the recent STEP-UP trial compared intensified semaglutide 7.2 mg with semaglutide 2.4 mg in adult patients with a BMI of 30 kg/m 2 and above, without diabetes

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In children receiving long-term risperidone, the ratio of Bacteroidetes to Firmicutes (two major bacterial groups in the gut) dropped significantly from 1.24 in psychiatric controls to just 0.20 in those who gained a lot of weight