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The Factors That Increase Cholesterol Levels The most common factors that bring those levels up are lifestyle routines that your daily life consists of, and they include: Poor diet consisting of ultra-processed foods, trans fats, and saturated fats Malnutrition Sedentary lifestyle and lack of exercise Insufficient sleep Smoking and excessive alcohol abuse Obesity and being overweight Type 2 diabetes Certain medications Genetic disorders ( familial hypercholesterolemia ) Most of these factors can be controlled and reversed by cleaning up your diet, paying more attention to developing better sleeping habits, increasing your level of activity, limiting your alcohol and cigarette use, as well as managing your stress and weight, maintaining a healthy body mass index (BMI)