They will help determine which medication is best based on specific medical needs
Beyond glycemic control, GLP-1RA-induced weight loss, averaging 6.3 kg over 2452 weeks, confers additional metabolic advantages, including improved lipid profiles, reduced insulin resistance, and decreased hypertension, each of which plays a crucial role in the prevention of diabetic complications [84]
Weaknesses The lack of required baseline lab work is concerning from a medical safety perspective
GLP-1 RAs also delay gastric emptying, which contributes to satiety but may exacerbate symptoms in patients with pre-existing gastroparesis ( Additionally, weight loss with GLP-1 RAs is accompanied by reductions in lean mass, with skeletal muscle accounting for approximately 15%40% of total weight loss (Pandey et al., 2024
Semaglutide also slows gastric emptyingthe rate at which food moves from the stomach into the small intestineparticularly during early treatment
Med (Baltim)