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The same study also revealed semaglutides efficacy compared with placebo, with 85% of participants losing at least 5% of their baseline body weight after treatment, compared with 31.5% on the dummy medication

Metabolic and bariatric surgery should be discussed with patients who have BMI 35 kg/m (regardless of comorbidities) or BMI 30-34.9 kg/m with metabolic disease, according to 2022 ASMBS/IFSO guidelines

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Recent research presented at Heart Failure 2024 highlights that semaglutide reduces the necessity for loop diuretics and their dosage while also positively impacting symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction (HFpEF), irrespective of their diuretic regimen