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P22389) during the course of this research

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Abbreviations AMPK AMP-activated protein kinase COX II Cytochrome c oxidase subunit II mtDNA Mitochondrial DNA NEFA Nonesterified fatty acid PCR Polymerase chain reaction PGC-1 Peroxisome proliferator-activated receptor- coactivator-1 RPE Rating of perceived exertion VAS visual analogue scale Additional file Footnotes Competing interests This study was supported in part by a research fund from the KOHJIN Life Sciences Company, Ltd

Well over 100 different mutations have been documented in cystinosis [8, 9]