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The top hit, REG4, is highly specific to these cells, reinforcing that they are the drug's key target

Endocrinology 143(11):43974408 Green BD, Mooney MH, Gault VA, Irwin N, Bailey CJ, Harriott P, Greer B, OHarte FP, Flatt PR (2004 Mar) N-terminal His(7)-modification of glucagon-like peptide-1(7-36) amide generates dipeptidyl peptidase IV-stable analogues with potent antihyperglycaemic activity

1 session weekly or fortnightly

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10.3389/fphar.2020.618787 62 Jamali-RaeufyN.KardgarS.BaluchnejadmojaradT.RoghaniM.GoudarziM

Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles