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10.1038/s41598-023-36602-6 140 TianZ.FanJ.ZhaoY.BiS.SiL.LiuQ

Brain health and dementia risk: promising but evolving Large observational studies have associated GLP-1 use with a lower risk of Alzheimers disease compared to some other diabetes treatments (Xie et al., 2023)

88 In terms of immune regulation, it has been documented that interleukin-4 (IL-4) and IL-13 inhibit the expression of GPX4 in some tissues (including heart, spleen, lung, and kidney), while the expression of ALOX15 increases, resulting in the massive production of arachidonic acid metabolites and inducing lipid peroxidation

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