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Since inflammatory activation is often accompanied by increased oxidative stress, we next investigated whether aloxistatin modulates reactive oxygen species (ROS) production in HCFs, as ROS serve as mediators linking inflammatory signaling to fibrotic remodeling through the activation of redox-related pathways [40]

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Aproximadamente el 70% de los pacientes con AOS tienen obesidad y en pacientes con obesidad grave la prevalencia de AOS vara entre el 40% y el 90%1,2