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FINE-ONE included adults (18 years) with type 1 diabetes and chronic kidney disease

Athletes nominated to participate in a biological passport programme, must make themselves available for all tests at times specified by the drug control officer

478 The gene encoding astrocyte-specific protein S100B is located in chromosome 21 and increased levels of S100B are characteristic for Down syndrome

DPP-4 inhibitors: Linagliptin: hepatobiliary excretion (no dose adjustment required in patients with renal impairment, making it preferred) Other DPP-4 inhibitors (sitagliptin, vildagliptin, saxagliptin, and alogliptin) are predominantly eliminated by the kidneys, so dosage must be adjusted in cases of severe renal dysfunction

A double-blind RCT (n=150) in patients receiving sagopilone chemotherapy showed no reduction in CIPN incidence with LC, although a slight decrease in severity was observed in ovarian cancer patients (not in prostate cancer patients)