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By utilizing patient-specific organoid models combined with real-time drug response monitoring, researchers can accelerate the discovery of clinically relevant CSC vulnerabilities and optimize treatment strategies before clinical translation

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doi: 10.1097/RUQ.0b013e3181b738a6

Upon further evaluation, the smaller brains of these littermates were likely due to an increase in caspase-3 activity by 53%, which was associated with a 46% increase in reactive oxidative species (ROS) levels

Shi and Holtzman, 2018

(3) various CLA isomers, and the exact molecular mechanisms by which CLAs positively influence oxidative stress, inflammation, body composition, and physical performance