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Recent research indicates that neuronal ATP and adenosine interact with their respective receptors-P2X and P2Y for ATP, and adenosine A 2A receptors (A 2A R) for adenosine-leading to pericyte contraction, which reduces CBF, or membrane hyperpolarization, which increases CBF [26, 87,88,89]

Thus, it would be beneficial to develop a senolytic that acts not only on ageing cells but also senescent cancer cells to prevent cancer recurrence or progression

All the authors have read and agreed to the published version of the manuscript

J Hazard Mater 175:651657

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It's a cornerstone of healthy cellular function, truly