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-butyrobetaine (-BB) toxicity in gbh-1 variants To explore whether excess -BB selectively causes negative fitness effects, gbh-1(ko), gbh-1(G247Vfs*6), gbh-1(G283R) , and gbh-1(D72G) strains were cultured in the presence of -BB, using the BW25113 E

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Doctors were initially unable to determine the cause, but he was eventually diagnosed with NAION in that eye

doi: 10.1111/j.1365-3059.2010.02340.x 43 KovacsI.DurnerJ.LindermayrC

Notable observations post-administration include a marked increase in daytime activity, the erasure of circadian rhythms ( Pharmacological intervention Experimental groups were established, each comprising 6 model mice and 6 control mice