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Supplementation of vitamin B2 has been associated with a reduction in the frequency of migraine attacks as well as a decrease in the use of medications that are typically given to help address migraine symptoms
or by disturbing the cytokine balance through the inflammation that is associated with infection
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For example, INT-777 and MN6, TGR5 selective agonists, stimulated GLP-1 secretion and improved insulin sensitivity in diet-induced obesity (DIO) mice [180, 181]
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