Bermans program is designed around this very principle
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That relative increase is clinically meaningful because it shifts our approach from assuming isolated complaints to actively tracking timing, triggers, and concomitant medicines
Recent research has identied glucagon as a key hor- mone that modulates postprandial amino acid metabolism, and the integrated action of GLP-1, GIP, and glucagon is required for proper disposal of glucose, lipids, and amino acids in response to a meal (Finan et al., 2016;Holst et al., 2017;M uller et al., 2017)
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Physicians who prescribe it do so entirely off-label, accepting medicolegal risk and the burden of informed consent