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In addition to cyclization, installation of non-natural staples to -helical peptide sequences has been demonstrated through thiol-ene chemistry
Reduced GSH was purchased from Sigma (G4251)
The performance metrics were estimated using 4-fold cross-validation, repeated 50 times, stratified by participant sex, age, and diagnosis
It has a trickle-down effect, said Dr
However, the same group reported decreased QA-immunoreactive microglia in the hippocampus, suggesting that QA expression in the brain may be region-specific or that hippocampal cell atrophy may have hindered its detection [63]
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