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Major adverse limb events in type 2 diabetes patients receiving glucagon-like peptide-1 receptor agonists versus sodium-glucose cotransporter 2 inhibitors: a retrospective multi-institutional study

The performance metrics were estimated using 4-fold cross-validation, repeated 50 times, stratified by participant sex, age, and diagnosis

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At conception and during the first trimester, hyperglycemia increases the risk of fetal malformations and intrauterine fetal demise (77)

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